Kinase profiling results of kinases in KIF 3LCDA_BDY (CSF1R, PDB code: 3LCD, chain A)
Template Kinase: CSF1R
Template inhibitor: Sunitinib

23 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C C
ABL1TK     
ALKTK     
EGFRTK     
ERBB2TK     
ERBB4TK     
FGFR1TK     
FGFR3TK     
IGF1RTK     
INSRTK     
JAK2TK     
JAK3TK     
METTK     
CSF1RTK     
KITTK     
PDGFRBTK     
SRCTK     
HCKTK     
LCKTK     
LYNTK     
PTK6TK     
TEKTK     
NTRK1TK     
BRAFTKL     

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
ABL1TK     
ALKTK     
CSF1RTK     
EGFRTK     
ERBB2TK     
ERBB4TK     
FGFR1TK     
FGFR3TK     
HCKTK     
IGF1RTK     
INSRTK     
JAK2TK     
JAK3TK     
KITTK     
LCKTK     
LYNTK     
METTK     
NTRK1TK     
PDGFRBTK     
PTK6TK     
SRCTK     
TEKTK     
BRAFTKL