Kinase profiling results of kinases in KIF 3GUBA_GUB (DAPK1, PDB code: 3GUB, chain A)
Template Kinase: DAPK1
Template inhibitor: 2,6,9-Trisubstituted purine deriv. 23

17 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CHEK1CAMK
DAPK1CAMK
PIM1CAMK
CHEK2CAMK
CDK2CMGC
CDK5CMGC
CDK9CMGC
CLK1CMGC
CLK4CMGC
MAPK1CMGC
AURKAOther
CAMKK2Other
TTKOther
ABL1TK
JAK2TK
LCKTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
CHEK1CAMK     
CHEK2CAMK     
DAPK1CAMK     
PIM1CAMK     
CDC2CMGC     
CDC2CMGC     
CDK2CMGC     
CDK5CMGC     
CDK9CMGC     
CLK1CMGC     
CLK4CMGC     
MAPK1CMGC     
AURKAOther     
CAMKK2Other     
TTKOther     
ABL1TK     
JAK2TK     
LCKTK