Kinase profiling results of kinases in KIF 2CKEA_IQU (DAPK2, PDB code: 2CKE, chain A)
Template Kinase: DAPK2
Template inhibitor: AEIQS

10 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
AKT2AGC
ROCK1AGC
ROCK2AGC
PRKCEAGC
PKN1AGC
PKN2AGC
RPS6KA5AGC
RPS6KA5CAMK
STK33CAMK
DAPK2CAMK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
AKT2AGC  
PKN1AGC  
PKN2AGC  
PRKCAAGC  
PRKCEAGC  
ROCK1AGC  
ROCK2AGC  
RPS6KA5AGC  
DAPK2CAMK  
STK33CAMK