Kinase profiling results of kinases in KIF 1YWNA_LIF (KDR, PDB code: 1YWN, chain A)
Template Kinase: KDR
Template inhibitor: AC1NS1DP

 17 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
ABL1TK 
DDR1TK 
EPHA3TK 
METTK 
MUSKTK 
KITTK 
PDGFRATK 
PDGFRBTK 
TEKTK 
TIE1TK 
NTRK2TK 
NTRK3TK 
FLT1TK 
FLT4TK 
KDRTK 
BRAFTKL 
RIPK1TKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
ABL1TK
EPHA3TK
FLT1TK
FLT4TK
KDRTK
KITTK
METTK
MUSKTK
NTRK2TK
NTRK3TK
PDGFRATK
PDGFRBTK
TEKTK
BRAFTKL