Kinase profiling results of kinases in KIF 2E2BA_406 (ABL1, PDB code: 2E2B, chain A)
Template Kinase: ABL1
Template inhibitor: Bafetinib

18 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C C C
MAPK14CMGC      
ABL1TK      
ABL2TK      
DDR1TK      
EPHA1TK      
EPHA3TK      
INSRTK      
CSF1RTK      
KITTK      
PDGFRATK      
PDGFRBTK      
LCKTK      
TEKTK      
TIE1TK      
NTRK2TK      
NTRK3TK      
KDRTK      
BRAFTKL      

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C C
MAPK14CMGC       
ABL1TK       
ABL2TK       
CSF1RTK       
EPHA1TK       
EPHA3TK       
INSRTK       
KDRTK       
KITTK       
LCKTK       
NTRK2TK       
NTRK3TK       
PDGFRATK       
PDGFRBTK       
TEKTK       
BRAFTKL