Kinase profiling results of kinases in KIF 2OO8X_RAJ (TEK, PDB code: 2OO8, chain X)
Template Kinase: TEK
Template inhibitor: RAJ

16 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C C C C C
ABL1TK        
ABL2TK        
DDR1TK        
EPHA1TK        
EPHA3TK        
INSRTK        
KITTK        
PDGFRATK        
PDGFRBTK        
LCKTK        
TEKTK        
TIE1TK        
NTRK2TK        
NTRK3TK        
KDRTK        
BRAFTKL        

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C C C
ABL1TK        
ABL2TK        
EPHA1TK        
EPHA3TK        
INSRTK        
KDRTK        
KITTK        
LCKTK        
NTRK2TK        
NTRK3TK        
PDGFRATK        
PDGFRBTK        
TEKTK        
BRAFTKL