Kinase profiling results of kinases in KIF 2OSCA_MUH (TEK, PDB code: 2OSC, chain A)
Template Kinase: TEK
Template inhibitor: 2osc

17 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C
ABL1TK    
ABL2TK    
DDR1TK    
EPHA1TK    
EPHA3TK    
INSRTK    
KITTK    
PDGFRATK    
PDGFRBTK    
LCKTK    
TEKTK    
TIE1TK    
NTRK2TK    
NTRK3TK    
FLT1TK    
KDRTK    
BRAFTKL    

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
ABL1TK     
ABL2TK     
EPHA1TK     
EPHA3TK     
FLT1TK     
INSRTK     
KDRTK     
KITTK     
LCKTK     
NTRK2TK     
NTRK3TK     
PDGFRATK     
PDGFRBTK     
TEKTK     
BRAFTKL