Kinase profiling results of kinases in KIF 2R3LA_SCW (CDK2, PDB code: 2R3L, chain A)
Template Kinase: CDK2
Template inhibitor: 2r3j

19 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CDK2CMGC 
CDK4CMGC 
CDC2L6CMGC 
CDK8CMGC 
CLK4CMGC 
GSK3BCMGC 
MAPK10CMGC 
MAPK14CMGC 
AURKAOther 
CHUKOther 
EIF2AK2Other 
DDR1TK 
PTK2TK 
JAK2TK 
METTK 
SRCTK 
LCKTK 
PTK6TK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
CDC2CMGC     
CDC2CMGC     
CDK2CMGC     
CDK4CMGC     
CLK4CMGC     
GSK3BCMGC     
MAPK10CMGC     
MAPK14CMGC     
AURKAOther     
CHUKOther     
JAK2TK     
LCKTK     
METTK     
PTK2TK     
PTK6TK     
SRCTK