Kinase profiling results of kinases in KIF 3G0EA_B49 (KIT, PDB code: 3G0E, chain A)
Template Kinase: KIT
Template inhibitor: Sunitinib

37 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C C
ABL1TK     
ABL2TK     
TNK1TK     
TNK2TK     
MATKTK     
DDR1TK     
EPHA3TK     
EPHA7TK     
EPHA8TK     
FGFR1TK     
FGFR2TK     
FGFR3TK     
FGFR4TK     
INSRTK     
JAK2TK     
MUSKTK     
CSF1RTK     
KITTK     
PDGFRATK     
PDGFRBTK     
FRKTK     
FGRTK     
FYNTK     
SRCTK     
YES1TK     
LCKTK     
LYNTK     
PTK6TK     
SRMSTK     
TEKTK     
TIE1TK     
NTRK2TK     
NTRK3TK     
FLT1TK     
FLT4TK     
KDRTK     
RIPK1TKL     

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C
ABL1TK      
ABL2TK      
CSF1RTK      
EPHA3TK      
EPHA7TK      
EPHA8TK      
FGFR1TK      
FGFR2TK      
FGFR3TK      
FGFR4TK      
FGRTK      
FLT1TK      
FLT4TK      
FRKTK      
FYNTK      
INSRTK      
JAK2TK      
KDRTK      
KITTK      
LCKTK      
LYNTK      
MATKTK      
MUSKTK      
NTRK2TK      
NTRK3TK      
PDGFRATK      
PDGFRBTK      
PTK6TK      
SRCTK      
SRMSTK      
TEKTK      
TNK2TK      
YES1TK