Kinase profiling results of kinases in KIF 2VD5A_BI8 (DMPK, PDB code: 2VD5, chain A)
Template Kinase: DMPK
Template inhibitor: Ro 31-7549

19 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
CITAGC  
DMPKAGC  
PRKCDAGC  
PRKCQAGC  
PKN2AGC  
RPS6KB1AGC  
CAMK2GCAMK  
CHEK1CAMK  
MARK2CAMK  
NUAK1CAMK  
NUAK2CAMK  
DAPK1CAMK  
DAPK2CAMK  
STK17ACAMK  
PHKG1CAMK  
PRKD2CAMK  
CHEK2CAMK  
SLKSTE  
STK10STE  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C
DMPKAGC      
PKN2AGC      
PRKCDAGC      
PRKCQAGC      
RPS6KB1AGC      
CAMK2GCAMK      
CHEK1CAMK      
CHEK2CAMK      
DAPK1CAMK      
DAPK2CAMK      
MARK2CAMK      
NUAK1CAMK      
NUAK2CAMK      
PHKG1CAMK      
PRKD2CAMK      
STK17ACAMK      
SLKSTE      
STK10STE