Kinase profiling results of kinases in KIF 3ANQA_EHB (DYRK1A, PDB code: 3ANQ, chain A)
Template Kinase: DYRK1A
Template inhibitor: TG003

 7 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CLK1CMGC
CLK2CMGC
CLK3CMGC
CLK4CMGC
DYRK1ACMGC
DYRK1BCMGC
DYRK2CMGC

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
CLK1CMGC 
CLK2CMGC 
CLK3CMGC 
CLK4CMGC 
DYRK1ACMGC 
DYRK1BCMGC 
DYRK2CMGC