Kinase profiling results of kinases in KIF 3GT8A_ANP (EGFR, PDB code: 3GT8, chain A)
Template Kinase: EGFR
Template inhibitor: Phosphoaminophosphonic Acid-Adenylate Ester

 22 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PDPK1AGC
RPS6KA1AGC
RPS6KA1CAMK
AURKAOther
OXSR1STE
STK24STE
ABL1TK
TNK2TK
ALKTK
EGFRTK
ERBB3TK
EPHA3TK
PTK2BTK
FGFR1TK
FGFR2TK
IGF1RTK
INSRTK
KITTK
RETTK
SRCTK
HCKTK
LCKTK
ZAP70TK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
PDPK1AGC
RPS6KA1AGC
AURKAOther
OXSR1STE
STK24STE
ABL1TK
ALKTK
EGFRTK
EPHA3TK
FGFR1TK
FGFR2TK
HCKTK
IGF1RTK
INSRTK
KITTK
LCKTK
PTK2BTK
RETTK
SRCTK
TNK2TK
ZAP70TK