Kinase profiling results of kinases in KIF 2A19B_ANP (EIF2AK2, PDB code: 2A19, chain B)
Template Kinase: EIF2AK2
Template inhibitor: Phosphoaminophosphonic Acid-Adenylate Ester

 14 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PDPK1AGC
DAPK1CAMK
MAPKAPK23
CDK2CMGC
CDK9CMGC
GSK3BCMGC
AURKAOther
EIF2AK2Other
PLK1Other
STK24STE
PTK2BTK
LCKTK
ZAP70TK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
GRK6AGC
PDPK1AGC
DAPK1CAMK
MAPKAPK2CAMK
CDK2CMGC
CDK9CMGC
GSK3BCMGC
AURKAOther
PLK1Other
STK24STE
LCKTK
PTK2BTK
ZAP70TK