Kinase profiling results of kinases in KIF 3DZQA_IFC (EPHA3, PDB code: 3DZQ, chain A)
Template Kinase: EPHA3
Template inhibitor: Nilotinib

9 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
ABL1TK 
ABL2TK 
EPHA1TK 
EPHA3TK 
LCKTK 
TEKTK 
TIE1TK 
KDRTK 
BRAFTKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
ABL1TK   
ABL2TK   
EPHA1TK   
EPHA3TK   
KDRTK   
LCKTK   
TEKTK   
BRAFTKL