Kinase profiling results of kinases in KIF 2VWVA_7X3 (EPHB4, PDB code: 2VWV, chain A)
Template Kinase: EPHB4
Template inhibitor: 2vwv

13 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
ALKTK  
EGFRTK  
EPHB4TK  
IGF1RTK  
INSRTK  
JAK1TK  
JAK2TK  
FYNTK  
SRCTK  
TEKTK  
KDRTK  
IRAK4TKL  
BRAFTKL  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C
ALKTK      
EGFRTK      
EPHB4TK      
FYNTK      
IGF1RTK      
INSRTK      
JAK1TK      
JAK2TK      
KDRTK      
SRCTK      
TEKTK      
BRAFTKL      
IRAK4TKL