Kinase profiling results of kinases in KIF 2VWWA_7X2 (EPHB4, PDB code: 2VWW, chain A)
Template Kinase: EPHB4
Template inhibitor: 2vww

12 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
ALKTK  
EGFRTK  
EPHB4TK  
FGFR1TK  
IGF1RTK  
INSRTK  
JAK1TK  
JAK2TK  
FYNTK  
SRCTK  
KDRTK  
BRAFTKL  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C C C
ALKTK        
EGFRTK        
EPHB4TK        
FGFR1TK        
FYNTK        
IGF1RTK        
INSRTK        
JAK1TK        
JAK2TK        
KDRTK        
SRCTK        
BRAFTKL