Kinase profiling results of kinases in KIF 3PP0A_03Q (ERBB2, PDB code: 3PP0, chain A)
Template Kinase: ERBB2
Template inhibitor: AZD_1152HQPA

 3 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
TNK2TK  
EGFRTK  
ERBB2TK  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
EGFRTK
ERBB2TK
TNK2TK