Kinase profiling results of kinases in KIF 3GQIA_ACP (FGFR1, PDB code: 3GQI, chain A)
Template Kinase: FGFR1
Template inhibitor: adenosine tetraphosphate

 13 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
AURKAOther
ALKTK
MERTKTK
EGFRTK
ERBB3TK
PTK2TK
FGFR1TK
FGFR2TK
IGF1RTK
INSRTK
LCKTK
ZAP70TK
IRAK4TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
AURKAOther
ALKTK
EGFRTK
FGFR1TK
FGFR2TK
IGF1RTK
INSRTK
LCKTK
MERTKTK
PTK2TK
ZAP70TK
IRAK4TKL