Kinase profiling results of kinases in KIF 3GQLA_GQL (FGFR1, PDB code: 3GQL, chain A)
Template Kinase: FGFR1
Template inhibitor: HMS3401N17

 14 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CDK2CMGC 
MAPK14CMGC 
CHUKOther 
EGFRTK 
FGFR1TK 
IGF1RTK 
KITTK 
PDGFRATK 
PDGFRBTK 
TEKTK 
NTRK1TK 
FLT4TK 
KDRTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
PRKCAAGC   
CDK2CMGC   
MAPK14CMGC   
CHUKOther   
EGFRTK   
FGFR1TK   
FLT4TK   
IGF1RTK   
KDRTK   
KITTK   
NTRK1TK   
PDGFRATK   
PDGFRBTK   
TEKTK