Kinase profiling results of kinases in KIF 1OUKA_084 (MAPK14, PDB code: 1OUK, chain A)
Template Kinase: MAPK14
Template inhibitor: 1ouk

 24 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
RPS6KA2AGC
RPS6KA2CAMK
PRKD3CAMK
CDK2CMGC
CDK3CMGC
CDK5CMGC
CDK9CMGC
CLK2CMGC
GSK3ACMGC
GSK3BCMGC
MAPK10CMGC
MAPK8CMGC
MAPK9CMGC
NLKCMGC
MAPK11CMGC
MAPK14CMGC
PLK1Other
FGFR1TK
FGFR2TK
FGRTK
FYNTK
SRCTK
YES1TK
LCKTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
RPS6KA2AGC    
PRKD3CAMK    
CDC2CMGC    
CDC2CMGC    
CDK2CMGC    
CDK3CMGC    
CDK5CMGC    
CDK9CMGC    
CLK2CMGC    
GSK3ACMGC    
GSK3BCMGC    
MAPK10CMGC    
MAPK11CMGC    
MAPK14CMGC    
MAPK8CMGC    
MAPK9CMGC    
NLKCMGC    
PLK1Other    
FGFR1TK    
FGFR2TK    
FGRTK    
FYNTK    
LCKTK    
SRCTK    
YES1TK