Kinase profiling results of kinases in KIF 2VX1A_7X8 (EPHB4, PDB code: 2VX1, chain A)
Template Kinase: EPHB4
Template inhibitor: DB07256

 19 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CSKTK
EPHA1TK
EPHA2TK
EPHA3TK
EPHA4TK
EPHA5TK
EPHA6TK
EPHB2TK
EPHB3TK
EPHB4TK
FGRTK
FYNTK
YES1TK
BLKTK
PTK6TK
BMXTK
TXKTK
ACVR1BTKL
TGFBR1TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
BLKTK 
BMXTK 
CSKTK 
EPHA1TK 
EPHA2TK 
EPHA3TK 
EPHA4TK 
EPHA5TK 
EPHA6TK 
EPHB2TK 
EPHB3TK 
EPHB4TK 
FGRTK 
FYNTK 
PTK6TK 
TXKTK 
YES1TK 
ACVR1BTKL 
TGFBR1TKL