KIDFamMap

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Kinase profiling results of kinases in KIF 3C4DA_325 (BRAF, PDB code: 3C4D, chain A)
Template Kinase: BRAF Template inhibitor: PLX4720	35 kinases in the family Kinase profiling results source 1. Davis et al. Nature Biotechnology.29, 1046-51 2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45 Similarity between template inhibitor and test compounds of profiling results Atom pair threshold: Checkmol threshold:

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM

>10uM

Kinase	Kinase group	C
AURKA	Other
AURKB	Other
AURKC	Other
NEK2	Other
STK36	Other
OXSR1	STE
SLK	STE
ABL1	TK
ABL2	TK
TNK2	TK
CSK	TK
DDR1	TK
EPHB6	TK
FES	TK
FGFR1	TK
FGFR2	TK
CSF1R	TK
KIT	TK
PDGFRB	TK
FRK	TK
FGR	TK
FYN	TK
SRC	TK
YES1	TK
BLK	TK
HCK	TK
LCK	TK
LYN	TK
PTK6	TK
SRMS	TK
KDR	TK
BRAF	TKL
RAF1	TKL
RIPK1	TKL
BMPR1B	TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%

100%

Kinase	Kinase group
AURKA	Other
AURKB	Other
AURKC	Other
NEK2	Other
OXSR1	STE
SLK	STE
ABL1	TK
ABL2	TK
BLK	TK
CSF1R	TK
CSK	TK
FES	TK
FGFR1	TK
FGFR2	TK
FGR	TK
FRK	TK
FYN	TK
HCK	TK
KDR	TK
KIT	TK
LCK	TK
LYN	TK
PDGFRB	TK
PTK6	TK
SRC	TK
SRMS	TK
TNK2	TK
YES1	TK
BRAF	TKL
RAF1	TKL