Kinase profiling results of kinases in KIF 3NYOA_AMP (GRK6, PDB code: 3NYO, chain A)
Template Kinase: GRK6
Template inhibitor: Adenosine monophosphate

 23 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
AKT2AGC
ROCK1AGC
PDPK1AGC
PRKCIAGC
STK11CAMK
CASKCAMK
DAPK1CAMK
MAPKAPK23
CHEK2CAMK
CDK2CMGC
CSNK2A1CMGC
GSK3BCMGC
MAPK10CMGC
MAPK12CMGC
AURKAOther
NEK7Other
PLK1Other
TTKOther
OXSR1STE
STK24STE
MAP2K1STE

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
AKT2AGC 
GRK6AGC 
PDPK1AGC 
PRKCIAGC 
ROCK1AGC 
SGK1AGC 
CHEK2CAMK 
DAPK1CAMK 
MAPKAPK2CAMK 
STK11CAMK 
CDK2CMGC 
CSNK2A1CMGC 
GSK3BCMGC 
MAPK10CMGC 
MAPK12CMGC 
AURKAOther 
NEK7Other 
PLK1Other 
TTKOther 
MAP2K1STE 
OXSR1STE 
STK24STE