Kinase profiling results of kinases in KIF 2I40A_BLZ (CDK2, PDB code: 2I40, chain A)
Template Kinase: CDK2
Template inhibitor: 2i40

 34 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
ROCK1AGC 
GRK4AGC 
GRK7AGC 
PRKCDAGC 
PKN2AGC 
RPS6KA4AGC 
RPS6KA4CAMK 
RPS6KA2AGC 
RPS6KA2CAMK 
RPS6KA3AGC 
RPS6KA6AGC 
RPS6KA6CAMK 
CAMK2ACAMK 
CAMK2BCAMK 
CAMK2DCAMK 
BRSK2CAMK 
MGC421053 
NUAK2CAMK 
DAPK1CAMK 
DAPK2CAMK 
DAPK3CAMK 
PIM1CAMK 
PIM3CAMK 
PRKD3CAMK 
CDK2CMGC 
CSNK2A1CMGC 
CSNK2A2CMGC 
NEK1Other 
NEK5Other 
NEK2Other 
NEK9Other 
PLK1Other 
PLK2Other 
PLK3Other 
SLKSTE 
STK10STE 
MAP3K9TKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
GRK4AGC
GRK7AGC
PKN2AGC
PRKCDAGC
ROCK1AGC
RPS6KA2AGC
RPS6KA3AGC
RPS6KA4AGC
RPS6KA6AGC
BRSK2CAMK
CAMK2ACAMK
CAMK2BCAMK
CAMK2DCAMK
DAPK1CAMK
DAPK2CAMK
DAPK3CAMK
NUAK2CAMK
PIM1CAMK
PIM3CAMK
PRKD3CAMK
CDK2CMGC
CSNK2A1CMGC
CSNK2A2CMGC
NEK1Other
NEK2Other
PLK1Other
PLK2Other
PLK3Other
SLKSTE
STK10STE
MAP3K9TKL