Kinase profiling results of kinases in KIF 3NYNA_SGV (GRK6, PDB code: 3NYN, chain A)
Template Kinase: GRK6
Template inhibitor: SMR000127424

 54 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
AKT1AGC 
CITAGC 
ROCK1AGC 
ROCK2AGC 
GRK1AGC 
GRK4AGC 
GRK7AGC 
MAST1AGC 
STK38AGC 
STK38LAGC 
PDPK1AGC 
PRKACAAGC 
PRKACBAGC 
PRKXAGC 
PRKCDAGC 
PRKCQAGC 
PRKG1AGC 
PRKG2AGC 
PKN2AGC 
CAMK4CAMK 
CAMK2ACAMK 
CHEK1CAMK 
DAPK1CAMK 
STK17ACAMK 
STK17BCAMK 
DCLK3CAMK 
MAPKAPK23 
PIM3CAMK 
PRKD1CAMK 
PRKD2CAMK 
PRKD3CAMK 
CHEK2CAMK 
CDK2CMGC 
CDK3CMGC 
CDC2L5CMGC 
CDKL2CMGC 
CDKL3CMGC 
CDKL5CMGC 
MAPK10CMGC 
MAPK12CMGC 
AURKAOther 
AURKBOther 
AURKCOther 
TTKOther 
STK36Other 
MAP3K1STE 
YSK4STE 
MAP3K2STE 
MAP3K3STE 
MAP3K4STE 
STK24STE 
STK25STE 
JAK3TK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
AKT1AGC 
GRK4AGC 
GRK6AGC 
GRK7AGC 
PDPK1AGC 
PKN2AGC 
PRKACAAGC 
PRKCDAGC 
PRKCQAGC 
PRKG1AGC 
PRKG2AGC 
PRKXAGC 
ROCK1AGC 
ROCK2AGC 
STK38AGC 
CAMK2ACAMK 
CAMK4CAMK 
CHEK1CAMK 
CHEK2CAMK 
DAPK1CAMK 
MAPKAPK2CAMK 
PIM3CAMK 
PRKD1CAMK 
PRKD2CAMK 
PRKD3CAMK 
STK17ACAMK 
CDK2CMGC 
CDK3CMGC 
MAPK10CMGC 
MAPK12CMGC 
AURKAOther 
AURKBOther 
AURKCOther 
TTKOther 
MAP3K2STE 
MAP3K3STE 
STK24STE 
STK25STE 
JAK3TK