Kinase profiling results of kinases in KIF 1OIQA_HDU (CDK2, PDB code: 1OIQ, chain A)
Template Kinase: CDK2
Template inhibitor: AC1L9L2U

14 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CHEK1CAMK
CDK2CMGC
CDK4CMGC
CDK5CMGC
GSK3ACMGC
GSK3BCMGC
MAPK1CMGC
MAPK10CMGC
MAPK8CMGC
MAPK9CMGC
AURKAOther
AURKBOther
FYNTK
ITKTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
CHEK1CAMK   
CDK2CMGC   
CDK4CMGC   
CDK5CMGC   
GSK3ACMGC   
GSK3BCMGC   
MAPK1CMGC   
MAPK10CMGC   
MAPK8CMGC   
MAPK9CMGC   
AURKAOther   
AURKBOther   
FYNTK   
ITKTK