Kinase profiling results of kinases in KIF 2FVDA_LIA (CDK2, PDB code: 2FVD, chain A)
Template Kinase: CDK2
Template inhibitor: [4-Amino-2-[(1-methylsulfonylpiperidin-4-yl)amino]pyrimidin-5-yl](2,3-difluoro-6-methoxyphenyl)methanone

 39 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
ROCK1AGC 
ROCK2AGC 
PKN2AGC 
CAMK2ACAMK 
CAMK2BCAMK 
CASKCAMK 
DCLK3CAMK 
CDK2CMGC 
CDK3CMGC 
CDK4CMGC 
CDK5CMGC 
CDK7CMGC 
CDK9CMGC 
CDC2L5CMGC 
PCTK1CMGC 
PCTK2CMGC 
PCTK3CMGC 
CDK15CMGC 
PFTK1CMGC 
CDK11ACMGC 
CDK11ACMGC 
CDKL5CMGC 
CLK1CMGC 
CLK2CMGC 
CLK3CMGC 
CLK4CMGC 
DYRK1ACMGC 
DYRK1BCMGC 
GSK3ACMGC 
GSK3BCMGC 
MAPK7CMGC 
MAPK15CMGC 
ICKCMGC 
MAKCMGC 
CAMKK2Other 
TTKOther 
SLKSTE 
ABL1TK 
TNNI3KTKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
PKN2AGC
ROCK1AGC
ROCK2AGC
CAMK2ACAMK
CAMK2BCAMK
CDC2CMGC
CDC2CMGC
CDK2CMGC
CDK3CMGC
CDK4CMGC
CDK5CMGC
CDK7CMGC
CDK9CMGC
CLK1CMGC
CLK2CMGC
CLK3CMGC
CLK4CMGC
DYRK1ACMGC
DYRK1BCMGC
GSK3ACMGC
GSK3BCMGC
CAMKK2Other
TTKOther
SLKSTE
ABL1TK