Kinase profiling results of kinases in KIF 3EJ1A_5BP (CDK2, PDB code: 3EJ1, chain A)
Template Kinase: CDK2
Template inhibitor: AC1OCFRV

 46 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
AKT1AGC 
AKT2AGC 
ROCK1AGC 
ROCK2AGC 
PDPK1AGC 
PRKCDAGC 
CHEK1CAMK 
NUAK1CAMK 
STK33CAMK 
DAPK1CAMK 
PIM1CAMK 
CHEK2CAMK 
CDK2CMGC 
CDK4CMGC 
CSNK2A1CMGC 
CSNK2A2CMGC 
CLK3CMGC 
CLK4CMGC 
GSK3ACMGC 
GSK3BCMGC 
MAPK8CMGC 
MAPK9CMGC 
MAPK14CMGC 
AURKAOther 
AURKBOther 
CHUKOther 
PLK1Other 
SLKSTE 
ABL2TK 
TNK2TK 
FERTK 
FGFR1TK 
JAK2TK 
JAK3TK 
FYNTK 
SRCTK 
YES1TK 
LCKTK 
BMXTK 
ITKTK 
NTRK2TK 
NTRK3TK 
IRAK4TKL 
MAP3K11TKL 
MAP3K9TKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
AKT1AGC 
AKT2AGC 
PDPK1AGC 
PRKCAAGC 
PRKCDAGC 
ROCK1AGC 
ROCK2AGC 
CHEK1CAMK 
CHEK2CAMK 
DAPK1CAMK 
NUAK1CAMK 
PIM1CAMK 
STK33CAMK 
CDK2CMGC 
CDK4CMGC 
CLK3CMGC 
CLK4CMGC 
CSNK2A1CMGC 
CSNK2A2CMGC 
GSK3ACMGC 
GSK3BCMGC 
MAPK14CMGC 
MAPK8CMGC 
MAPK9CMGC 
AURKAOther 
AURKBOther 
CHUKOther 
PLK1Other 
SLKSTE 
ABL2TK 
BMXTK 
FERTK 
FGFR1TK 
FYNTK 
ITKTK 
JAK2TK 
JAK3TK 
LCKTK 
NTRK2TK 
NTRK3TK 
SRCTK 
TNK2TK 
YES1TK 
IRAK4TKL 
MAP3K11TKL 
MAP3K9TKL