Kinase profiling results of kinases in KIF 3FUPA_MI1 (JAK2, PDB code: 3FUP, chain A)
Template Kinase: JAK2
Template inhibitor: CP690550

 16 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
PDPK1AGC 
PKN1AGC 
DCLK3CAMK 
CDK2CMGC 
GSK3ACMGC 
MAP4K2STE 
STK3STE 
STK4STE 
ABL1TK 
TNK1TK 
JAK1TK 
JAK2TK 
JAK3TK 
RETTK 
FYNTK 
LCKTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
PDPK1AGC 
PKN1AGC 
CDK2CMGC 
GSK3ACMGC 
MAP4K2STE 
STK3STE 
STK4STE 
ABL1TK 
FYNTK 
JAK1TK 
JAK2TK 
JAK3TK 
LCKTK 
RETTK