Kinase profiling results of kinases in KIF 3KVWA_IRB (DYRK2, PDB code: 3KVW, chain A)
Template Kinase: DYRK2
Template inhibitor: CI_1040

15 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PDPK1AGC
BRSK1CAMK
BRSK2CAMK
NUAK1CAMK
CDK2CMGC
CDK3CMGC
CDK5CMGC
DYRK2CMGC
GSK3ACMGC
GSK3BCMGC
AURKAOther
AURKBOther
AURKCOther

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
PDPK1AGC   
BRSK1CAMK   
BRSK2CAMK   
NUAK1CAMK   
CDC2CMGC   
CDC2CMGC   
CDK2CMGC   
CDK3CMGC   
CDK5CMGC   
CDK6CMGC   
CDK6CMGC   
DYRK2CMGC   
GSK3ACMGC   
GSK3BCMGC   
AURKAOther   
AURKBOther   
AURKCOther