Kinase profiling results of kinases in KIF 3LFQA_A28 (CDK2, PDB code: 3LFQ, chain A)
Template Kinase: CDK2
Template inhibitor: DNC010588

10 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CDK2CMGC 
CDK4CMGC 
GSK3ACMGC 
GSK3BCMGC 
MAPK1CMGC 
MAPK10CMGC 
MAPK14CMGC 
AURKAOther 
LCKTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
CDC2CMGC   
CDC2CMGC   
CDK2CMGC   
CDK4CMGC   
GSK3ACMGC   
GSK3BCMGC   
MAPK1CMGC   
MAPK10CMGC   
MAPK14CMGC   
AURKAOther   
LCKTK