Kinase profiling results of kinases in KIF 3LFSA_A07 (CDK2, PDB code: 3LFS, chain A)
Template Kinase: CDK2
Template inhibitor: DNC010588

14 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
MARK1CAMK 
PIM2CAMK 
CDK2CMGC 
CDK4CMGC 
GSK3ACMGC 
GSK3BCMGC 
MAPK1CMGC 
MAPK10CMGC 
MAPK14CMGC 
AURKAOther 
PTK2TK 
SRCTK 
LCKTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
MARK1CAMK    
PIM2CAMK    
CDC2CMGC    
CDC2CMGC    
CDK2CMGC    
CDK4CMGC    
GSK3ACMGC    
GSK3BCMGC    
MAPK1CMGC    
MAPK10CMGC    
MAPK14CMGC    
AURKAOther    
LCKTK    
PTK2TK    
SRCTK