Kinase profiling results of kinases in KIF 3SD0A_TSK (GSK3B, PDB code: 3SD0, chain A)
Template Kinase: GSK3B
Template inhibitor: 3-(5-Fluoro-6-Iodo-1-Methyl-1h-Indol-3-Yl)-4-(7-Methoxy-1-Benzofuran-3-Yl)-1h-Pyrrole-2,5-Dione

 9 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CDK2CMGC
CDK3CMGC
CDK5CMGC
CDK9CMGC
GSK3BCMGC
AURKAOther

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
PRKCAAGC 
CDC2CMGC 
CDC2CMGC 
CDK2CMGC 
CDK3CMGC 
CDK5CMGC 
CDK6CMGC 
CDK6CMGC 
CDK9CMGC 
GSK3BCMGC 
AURKAOther