Kinase profiling results of kinases in KIF 1QCFA_PP1 (HCK, PDB code: 1QCF, chain A)
Template Kinase: HCK
Template inhibitor: PP1

 31 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
RPS6KA1AGC  
RPS6KA1CAMK  
RPS6KA6AGC  
RPS6KA6CAMK  
CHEK1CAMK  
MAPK1CMGC  
MAPK14CMGC  
ABL1TK  
TNK2TK  
CSKTK  
EGFRTK  
ERBB2TK  
EPHB1TK  
EPHB2TK  
EPHB3TK  
EPHB4TK  
IGF1RTK  
JAK2TK  
JAK3TK  
TYK2TK  
KITTK  
PDGFRBTK  
RETTK  
FYNTK  
SRCTK  
YES1TK  
HCKTK  
LCKTK  
PTK6TK  
SYKTK  
BMXTK  
BTKTK  
TXKTK  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
RPS6KA1AGC   
RPS6KA6AGC   
CHEK1CAMK   
MAPK1CMGC   
MAPK14CMGC   
ABL1TK   
BMXTK   
BTKTK   
CSKTK   
EGFRTK   
EPHB1TK   
EPHB2TK   
EPHB3TK   
EPHB4TK   
ERBB2TK   
FYNTK   
HCKTK   
IGF1RTK   
JAK2TK   
JAK3TK   
KITTK   
LCKTK   
PDGFRBTK   
PTK6TK   
RETTK   
SRCTK   
SYKTK   
TNK2TK   
TXKTK   
TYK2TK   
YES1TK