Kinase profiling results of kinases in KIF 2HCKA_QUE (HCK, PDB code: 2HCK, chain A)
Template Kinase: HCK
Template inhibitor: quercetin

 8 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CDK2CMGC
CDK5CMGC
MAPK14CMGC
ABL1TK
EGFRTK
INSRTK
SRCTK
HCKTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
CDK2CMGC
CDK5CMGC
MAPK14CMGC
ABL1TK
EGFRTK
HCKTK
INSRTK
SRCTK