Kinase profiling results of kinases in KIF 1K3AA_ACP (IGF1R, PDB code: 1K3A, chain A)
Template Kinase: IGF1R
Template inhibitor: adenosine tetraphosphate

 8 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
RPS6KA1AGC
RPS6KA1CAMK
ALKTK
FGFR2TK
IGF1RTK
METTK
RETTK
ZAP70TK
IRAK4TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
RPS6KA1AGC
ALKTK
FGFR2TK
IGF1RTK
METTK
RETTK
ZAP70TK
IRAK4TKL