Kinase profiling results of kinases in KIF 1YOMA_P01 (SRC, PDB code: 1YOM, chain A)
Template Kinase: SRC
Template inhibitor: Lopac0_000938

27 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CHEK1CAMK
CDK5CMGC
CDK9CMGC
PCTK1CMGC
MAPK14CMGC
ABL1TK
ABL2TK
TNK2TK
ALKTK
EGFRTK
INSRTK
INSRRTK
JAK2TK
MUSKTK
FGRTK
FYNTK
SRCTK
YES1TK
HCKTK
LCKTK
LYNTK
BTKTK
TXKTK
NTRK1TK
NTRK2TK
NTRK3TK
IRAK4TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C C
CHEK1CAMK       
CDK5CMGC       
CDK9CMGC       
MAPK14CMGC       
ABL1TK       
ABL2TK       
ALKTK       
BTKTK       
EGFRTK       
FGRTK       
FYNTK       
HCKTK       
INSRTK       
INSRRTK       
JAK2TK       
LCKTK       
LYNTK       
MUSKTK       
NTRK1TK       
NTRK2TK       
NTRK3TK       
SRCTK       
TNK2TK       
TXKTK       
YES1TK       
IRAK4TKL