Kinase profiling results of kinases in KIF 3BPRA_OLP (MERTK, PDB code: 3BPR, chain A)
Template Kinase: MERTK
Template inhibitor: compound 52

9 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
ALKTK
MERTKTK
INSRTK
INSRRTK
MUSKTK
BTKTK
NTRK1TK
NTRK2TK
NTRK3TK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
ALKTK     
BTKTK     
INSRTK     
INSRRTK     
MERTKTK     
MUSKTK     
NTRK1TK     
NTRK2TK     
NTRK3TK