Kinase profiling results of kinases in KIF 3IOKA_1P6 (JAK2, PDB code: 3IOK, chain A)
Template Kinase: JAK2
Template inhibitor: PTK_787

16 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CDK2CMGC 
CDK4CMGC 
GSK3BCMGC 
AURKBOther 
ABL1TK 
EGFRTK 
PTK2TK 
IGF1RTK 
JAK2TK 
JAK3TK 
PDGFRBTK 
SRCTK 
LCKTK 
NTRK1TK 
IRAK4TKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C C
CDC2CMGC       
CDC2CMGC       
CDK2CMGC       
CDK4CMGC       
GSK3BCMGC       
AURKBOther       
ABL1TK       
EGFRTK       
IGF1RTK       
JAK2TK       
JAK3TK       
LCKTK       
NTRK1TK       
PDGFRBTK       
PTK2TK       
SRCTK       
IRAK4TKL