Kinase profiling results of kinases in KIF 3KRRA_DQX (JAK2, PDB code: 3KRR, chain A)
Template Kinase: JAK2
Template inhibitor: DQX

8 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
ABL1TK  
EGFRTK  
JAK1TK  
JAK2TK  
JAK3TK  
RETTK  
LCKTK  
BRAFTKL  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
ABL1TK
EGFRTK
JAK1TK
JAK2TK
JAK3TK
LCKTK
RETTK
BRAFTKL