Kinase profiling results of kinases in KIF 3LXKA_MI1 (JAK3, PDB code: 3LXK, chain A)
Template Kinase: JAK3
Template inhibitor: CP690550

5 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CDK2CMGC 
JAK1TK 
JAK2TK 
JAK3TK 
RETTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
CDK2CMGC 
JAK1TK 
JAK2TK 
JAK3TK 
RETTK