Kinase profiling results of kinases in KIF 2P2IA_608 (KDR, PDB code: 2P2I, chain A)
Template Kinase: KDR
Template inhibitor: nicotinamide 35

15 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
ABL1TK 
ABL2TK 
DDR1TK 
PTK2BTK 
FGFR1TK 
METTK 
KITTK 
PDGFRATK 
PDGFRBTK 
LCKTK 
TEKTK 
FLT1TK 
FLT4TK 
KDRTK 
BRAFTKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
ABL1TK   
ABL2TK   
FGFR1TK   
FLT1TK   
FLT4TK   
KDRTK   
KITTK   
LCKTK   
METTK   
PDGFRATK   
PDGFRBTK   
PTK2BTK   
TEKTK   
BRAFTKL