Kinase profiling results of kinases in KIF 3CJFA_SAV (KDR, PDB code: 3CJF, chain A)
Template Kinase: KDR
Template inhibitor: GW_2580

11 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
ALKTK  
EPHB4TK  
IGF1RTK  
INSRTK  
METTK  
TEKTK  
NTRK1TK  
NTRK2TK  
NTRK3TK  
KDRTK  
BRAFTKL  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
ALKTK     
EPHB4TK     
IGF1RTK     
INSRTK     
KDRTK     
METTK     
NTRK1TK     
NTRK2TK     
NTRK3TK     
TEKTK     
BRAFTKL