Kinase profiling results of kinases in KIF 3EWHA_K11 (KDR, PDB code: 3EWH, chain A)
Template Kinase: KDR
Template inhibitor: k11

17 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C
ABL1TK   
ABL2TK   
DDR1TK   
EPHA1TK   
FGFR1TK   
METTK   
KITTK   
PDGFRATK   
PDGFRBTK   
LCKTK   
TEKTK   
TIE1TK   
FLT1TK   
FLT4TK   
KDRTK   
BRAFTKL   
RIPK1TKL   

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
ABL1TK   
ABL2TK   
EPHA1TK   
FGFR1TK   
FLT1TK   
FLT4TK   
KDRTK   
KITTK   
LCKTK   
METTK   
PDGFRATK   
PDGFRBTK   
TEKTK   
BRAFTKL