Kinase profiling results of kinases in KIF 1QPCA_ANP (LCK, PDB code: 1QPC, chain A)
Template Kinase: LCK
Template inhibitor: Phosphoaminophosphonic Acid-Adenylate Ester

 26 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
DAPK1CAMK
CDK2CMGC
AURKAOther
NEK2Other
EIF2AK2Other
OXSR1STE
STK24STE
ABL1TK
TNK2TK
ALKTK
EGFRTK
ERBB3TK
EPHA2TK
EPHA3TK
PTK2BTK
FGFR1TK
FGFR2TK
IGF1RTK
INSRTK
KITTK
RETTK
SRCTK
HCKTK
LCKTK
ZAP70TK
IRAK4TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
DAPK1CAMK
CDK2CMGC
AURKAOther
NEK2Other
OXSR1STE
STK24STE
ABL1TK
ALKTK
EGFRTK
EPHA2TK
EPHA3TK
FGFR1TK
FGFR2TK
HCKTK
IGF1RTK
INSRTK
KITTK
LCKTK
PTK2BTK
RETTK
SRCTK
TNK2TK
ZAP70TK
IRAK4TKL