Kinase profiling results of kinases in KIF 1QPEA_PP2 (LCK, PDB code: 1QPE, chain A)
Template Kinase: LCK
Template inhibitor: AG 1879

29 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
MAPK14CMGC 
EIF2AK2Other 
ABL1TK 
TNK2TK 
CSKTK 
EGFRTK 
EPHA1TK 
EPHA2TK 
EPHA4TK 
EPHA5TK 
EPHA6TK 
EPHB1TK 
EPHB2TK 
EPHB3TK 
EPHB4TK 
PDGFRBTK 
RETTK 
FYNTK 
SRCTK 
YES1TK 
HCKTK 
LCKTK 
PTK6TK 
SYKTK 
BMXTK 
BTKTK 
TXKTK 
TGFBR1TKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C
CDC2CMGC      
CDC2CMGC      
MAPK14CMGC      
ABL1TK      
BMXTK      
BTKTK      
CSKTK      
EGFRTK      
EPHA1TK      
EPHA2TK      
EPHA4TK      
EPHA5TK      
EPHA6TK      
EPHB1TK      
EPHB2TK      
EPHB3TK      
EPHB4TK      
FYNTK      
HCKTK      
LCKTK      
PDGFRBTK      
PTK6TK      
RETTK      
SRCTK      
SYKTK      
TNK2TK      
TXKTK      
YES1TK      
TGFBR1TKL