Kinase profiling results of kinases in KIF 2OF4A_979 (LCK, PDB code: 2OF4, chain A)
Template Kinase: LCK
Template inhibitor: DB07297

 14 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CDK2CMGC
MAPK14CMGC
AURKAOther
CHUKOther
TNK2TK
EGFRTK
FGFR1TK
JAK2TK
PDGFRBTK
SRCTK
LCKTK
SYKTK
ZAP70TK
IRAK4TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
CDK2CMGC
MAPK14CMGC
AURKAOther
CHUKOther
EGFRTK
FGFR1TK
JAK2TK
LCKTK
PDGFRBTK
SRCTK
SYKTK
TNK2TK
ZAP70TK
IRAK4TKL