Kinase profiling results of kinases in KIF 3AC1A_KZI (LCK, PDB code: 3AC1, chain A)
Template Kinase: LCK
Template inhibitor: Staurosporine

11 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CDK2CMGC 
MAPK14CMGC 
AURKAOther 
JAK2TK 
CSF1RTK 
LCKTK 
SYKTK 
ZAP70TK 
ITKTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
PRKCBAGC   
PRKCBAGC   
CDC2CMGC   
CDC2CMGC   
CDK2CMGC   
MAPK14CMGC   
AURKAOther   
CSF1RTK   
ITKTK   
JAK2TK   
LCKTK   
SYKTK   
ZAP70TK