Kinase profiling results of kinases in KIF 3AC8A_KSK (LCK, PDB code: 3AC8, chain A)
Template Kinase: LCK
Template inhibitor: Staurosporine

12 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CDK2CMGC 
MAPK14CMGC 
AURKAOther 
NEK2Other 
TNK2TK 
CSF1RTK 
LCKTK 
SYKTK 
ZAP70TK 
BTKTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
PRKCBAGC    
PRKCBAGC    
CDC2CMGC    
CDC2CMGC    
CDK2CMGC    
MAPK14CMGC    
AURKAOther    
NEK2Other    
BTKTK    
CSF1RTK    
LCKTK    
SYKTK    
TNK2TK    
ZAP70TK