Kinase profiling results of kinases in KIF 3KXZA_925 (LCK, PDB code: 3KXZ, chain A)
Template Kinase: LCK
Template inhibitor: 2e9n

 12 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CDK2CMGC
MAPK14CMGC
AURKAOther
ABL1TK
JAK2TK
PDGFRATK
FYNTK
SRCTK
HCKTK
LCKTK
BRAFTKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
PRKCAAGC 
CDK2CMGC 
MAPK14CMGC 
AURKAOther 
ABL1TK 
FYNTK 
HCKTK 
JAK2TK 
LCKTK 
PDGFRATK 
SRCTK 
BRAFTKL